Test S of Haplotype Concordance and Discordance
نویسندگان
چکیده
منابع مشابه
A New S-test for Haplotype Analysis: Concordance and Discordance
A new test of inheritance, S, is proposed, which uses information from affected as well as unaffected siblings in the fam­ ily. The siblings are analyzed in terms of similarities of haplotypes. The distribution of the proposed S­test is derived under the null hypothesis of random inheritance. Mean and variance are obtained for the distribution. The test is then applied to data sets publ...
متن کاملTest S of Haplotype Concordance and Discordance
The test presented here is based upon the proband and his/her affected as well as unaffected siblings. Here, the siblings are analyzed in terms of similarities of haplotypes. The proposed ‘S’ test is used in testing hypothesis that a particular disease has random pattern of inheritance against the alternative hypothesis that it has non-random pattern of inheritance. Probability distribution, me...
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ژورنال
عنوان ژورنال: Pakistan Journal of Statistics and Operation Research
سال: 2007
ISSN: 2220-5810,1816-2711
DOI: 10.18187/pjsor.v3i1.76